Impaired proteostasis and autophagy are two intricately linked primary hallmarks of ageing. Autophagy is the process by which cells break down and recycle their components.Cellular waste…
Protection for the ends of our genetic material Each of us begins life as a single cell, which grows to form an entire organism. This process requires many, many cell divisions to produce the ~10…
Epigenetic markers control gene activity The blueprints for all the proteins that keep our cells running are stored in the DNA. To make the DNA fit in the cell nucleus, it is wrapped around…
Our genetic material is constantly at risk The DNA in each of our cells is damaged more than 100,000 times every day. That's an average of more than once per second! Since we are made up of over…
Ageing is caused by only five biological processes Although ageing has been linked to a host of diseases, scientists have surprisingly found that ageing itself is caused by only five core molecular…
Record holders for long life
For humans, the longest recorded lifespan is 122 years and 164 days. This record is held by Jeanne Calment, a French supercentenarian who was born in 1875 and died in…
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We need to extend our health span Over the last 150 years or so, our lifespan has more than doubled. Major advances in modern medicine such as better hygiene, vaccines and antibiotics are…
