Videos about ageing

Ageing affects us all, but why does it happen?

This video explains the biological mechanisms of ageing and how researchers at the Centre for Healthy Ageing (CHA) in Mainz are working to better understand these processes in order to promote healthy ageing.

What causes DNA damage and how can this lead to ageing? How do cells repair their DNA and why is this important for healthy ageing? Watch this video to find out!

At the Centre for Healthy Ageing (CHA) in Mainz, we investigate the mechanisms that protect our DNA and help keep cells healthy as they age.

Can scientists ‘measure’ how healthy you are just by looking at your DNA?

In this video, we explain how CHA scientists use epigenetic markers to measure biological age and gain insights into how we can age healthily.

What are R-loops, and why do they matter for ageing? In this video, the Research Training Group 4R explains how these RNA:DNA structures influence genome stability and may contribute to ageing and age-related diseases. This research could lead to future therapies to delay ageing and treat diseases such as cancer.

Spiegel-bestselling author Nina Ruge talks to Prof. Dorothee Dormann at the CHA about her research on amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), as well as new starting points for therapies and the importance of her work for understanding Alzheimer's disease.

Spiegel-bestselling author Nina Ruge talks to Prof. Peter Baumann, a Scientific Director of the CHA, about his research on the regulation of the enzyme telomerase, the impact of stress on telomere integrity and how his work creates opportunities for novel therapies.

“Don't be afraid of getting older!” Host Nina Ruge dives into the exciting world of ageing research with Prof. Christof Niehrs (Director of the Institute of Molecular Biology (IMB), Mainz), Prof. Brian Luke (Adjunct Director, IMB), and Kristi Jensen (PhD student, International PhD Programme). They discuss key questions such as: which scientific approaches promote a long, healthy life? Why do some people age more healthily than others?

Researchers at the CHA discuss their research on the causes of ageing, how some people live to extreme ages in good health, and what causes age-related diseases. 

An interview by Günther Gerhardt (Chairman of the Rhineland-Palatinate Senior Citizens' Association) with Prof. Christof Niehrs (Director of the CHA and Institute of Molecular Biology (IMB)) and Dr. Max Reuter (Team leader, IMB).

Spiegel-bestselling author Nina Ruge speaks to scientists about their latest findings on healthy ageing and longevity at the Aging Research and Drug Discovery Meeting (ARDD) in Copenhagen, Denmark. 

An interview with Prof. Dorothee Dormann at the CHA, by the Fritz Thyssen Stiftung Journal. Dorothee discusses her research on the causes of neurodegenerative diseases such as motor neuron disease and dementia.