Universal Mechanisms of Ageing in Metazoans
We are interested in conserved mechanisms that drive the ageing process in animals. Phylogenomic comparisons in our laboratory have yielded the first…
Research at the CHA covers both basic and clinical research, ranging from DNA repair, telomere biology and epigenetics to immunology, cancer and cardiovascular biology,…
The Blood Brain Barrier in Neurodegenerative Diseases
Our research team focuses on preclinical aspects of neurodegenerative diseases. We use in vitro and in vivo model systems for Alzheimer’s…
Clinical Epidemiology & Systems Medicine in Ageing
Preventive Cardiology and Preventive Medicine Our team is dedicated to studying common, complex ageing-related diseases that impose a high burden on…
Evidence Syntheses (Systematic Reviews & Meta-analyses) in Resilience & Ageing Research
With the exponential growth in the number of scientific publications, it is becoming increasingly difficult…
The interplay between heterochromatin, the stress response & premature ageing
The separation of our genome into euchromatin and heterochromatin is essential for faithfully orchestrating gene…
Molecular Basis of Brain Ageing
My group uses Drosophila as a model to investigate the biology of normal brain ageing. Specifically, we work to identify the molecular players and neural…
