Traumatic, Ischemic & Haemorrhagic Brain Injury & Brain Tumour
The main research interests of my group are the pathophysiology and treatment of neurotraumatic, ischemic and haemorrhagic brain injury…
Synaptic Function in the Adult & Ageing Brain
Synaptic communication changes with brain development and ageing. We work on the mechanisms of neuronal communication in the adult and aged mouse brain.…
Age-associated alterations in the immune system, also known as immunosenescence, can lead to a progressive loss of the immune system's ability to respond and develop immunity against diseases,…
Computational Immunogenomics
I am a computational immune-biologist focusing on the interaction of pathogens, diseased cells and the host immune system. My core expertise includes the…
DNA Damage Signalling in Cell Fate Control & Cancer
Dysfunction of the DNA damage response is a driving force for genome instability and cancer. Cells sense DNA damage through specific sensor…
Vascular Ageing
Vascular ageing contributes to the age-dependent rise of hypertension and atherosclerotic diseases. Increased arterial stiffness and impaired vascular function are the two most…
Intrinsically disordered proteins (IDPs) are most infamous for their involvement in neurodegenerative diseases, such as Alzheimer’s, Parkinson’s and Huntington’s disease. Almost paradoxically,…
Experimental Traumatic Brain Injury
Traumatic brain injury (TBI) is one of the leading causes of death and disability. It can result in permanent neurological impairment and increases the risk for…
