23 Feb 2023
As part of the ReALity workshop series, the 1st Proteostasis Network Mainz (PNM) Workshop on “Proteostasis Research in Health, Ageing & Disease” will take place on 23 February 2023…
Structural Chronobiology
Physiological processes that are regulated on a daily cycle, so-called circadian rhythms, can be found in all kingdoms of life. In humans, the circadian clock regulates many…
Systemic Mechanisms of Cognitive Resilient Ageing
About 20% of the ageing population compensate for average age-dependent decline (i.e. normal ageing) and show cognitive function comparable to…
Human Microbiome Ecology
Our research focuses on understanding the ecological dynamics of human gut-associated microbial communities in healthy host-microbiome homeostasis and how their disturbance…
15 Feb 2023
The International PhD Programme (IPP) holds regular symposia on key focus topics to promote exchange and encourage collaborations between participating research groups. This 1-day…
Haematopoietic Stem Cell Ageing, Blood Malignancies & Immune Escape
Haematopoiesis is required for the daily regeneration of blood and immune cells throughout life. This process is tightly regulated…
Physiological and Induced Neurogenesis in the Adult and Ageing Brain
For most parts of the brain, neurogenesis ceases forever with the end of embryonic development. In the adult brain, only the…
Genome Regulation by Chromatin Remodelling in Development, Ageing and Disease
The packaging of genomic DNA into chromatin enables its incorporation into the nucleus and provides a means of…
Immunological Consequences of Age-Related Changes in Proteostasis
T cells are crucially involved in the surveillance of tissues to eliminate infected or transformed cells. This function depends on…
